Lithium Oral Route Side Effects
The very first of these helped to convince the scientific and clinical community (Baastrup et al. 1970). In addition to its potentially toxic effects, lithium becoming an unpatentable natural solution with limited commercial interest had difficulties in attracting in depth help for research or clinical promotion by pharmaceutical corporations. The use of lithium salts to treat mania was rediscovered by the Australian psychiatrist John Cade in 1949. Cade was injecting rodents with urine extracts taken from schizophrenic sufferers, in an attempt to isolate a metabolic compound which might be causing mental symptoms. Considering that uric acid in gout was identified...