Healthcare Oxygen Gas Cylinders Marketplace Report 2022: Market
The transcription factor hypoxia-inducible element 1α (HIF-1α), the most recognized mediator of hypoxic responses, plays a central role in stimulating neovascularization in tumours to enhance oxygen and nutrient supply4. Paradoxically, these vessels are typically irregularly organized (e.g., twisted, hyperpermeable and blind-ended structures) and have defects in oxygen diffusion or perfusion5, resulting in expansions of hypoxic regions in tumours. These findings inspired the exploration of technologies to convert hypoxic microenvironments into hyperoxic microenvironments for tumour biology or therapy studies. Scientists at Mount Sinai say they have published one of the very first studies to demonstrate the importance of reactive oxygen species...